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Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

Diabetes in nonobese diabetic (NOD) mice is a T cell-dependent autoimmune disease. The destructive activities of autoreactive T cells have been shown to be tightly regulated by effector molecules. In particular, T helper (Th) 1 cytokines have been linked to diabetes pathogenesis, whereas Th2 cytokin...

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Bibliografiska uppgifter
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192796/
https://ncbi.nlm.nih.gov/pubmed/9064326
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