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The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB
Opportunistic infections, such as aspergillosis, are among the most serious complications suffered by immunocompromised patients. Aspergillus fumigatus and other pathogenic fungi synthesize a toxic epipolythiodioxopiperazine metabolite called gliotoxin. Gliotoxin exhibits profound immunosuppressive...
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| Формат: | Artigo |
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| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192527/ https://ncbi.nlm.nih.gov/pubmed/8666939 |
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