تحميل...
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
Recently, a severe combined immunodeficiency syndrome with a deficiency of CD8+ peripheral T cells and a TCR signal transduction defect in peripheral CD4+ T cells was associated with mutations in ZAP-70. Since TCR signaling is required in developmental decisions resulting in mature CD4 (and CD8) T c...
محفوظ في:
| التنسيق: | Artigo |
|---|---|
| اللغة: | Inglês |
| منشور في: |
The Rockefeller University Press
1995
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192291/ https://ncbi.nlm.nih.gov/pubmed/7561679 |
| الوسوم: |
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