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The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

The dose of foreign antigen can influence whether a cell-mediated or humoral class of immune response is elicited, and this may be largely accounted for by the development of CD4+ T helper cells (Th) producing distinct sets of cytokines. The ability of antigen dose to direct the development of a Th1...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192218/
https://ncbi.nlm.nih.gov/pubmed/7595228
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