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Cross-linking of major histocompatibility complex class II molecules by staphylococcal enterotoxin A superantigen is a requirement for inflammatory cytokine gene expression

Staphylococcal enterotoxin A (SEA) has two distinct binding sites for major histocompatibility complex (MHC) class II molecules. The aspartic acid located at position 227 (D227) in the COOH terminus of SEA is one of the three residues involved in its interaction with the DR beta chain, whereas the p...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192187/
https://ncbi.nlm.nih.gov/pubmed/7595227
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