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Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors

We reported that interleukin (IL) 6 alone cannot induce osteoclast formation in cocultures of mouse bone marrow and osteoblastic cells, but soluble IL-6 receptor (IL-6R) strikingly triggered osteoclast formation induced by IL-6. In this study, we examined the mechanism of osteoclast formation by IL-...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192181/
https://ncbi.nlm.nih.gov/pubmed/7595216
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