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The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

In mice, natural resistance or susceptibility to infection with intracellular parasites is determined by a locus or group of loci on chromosome 1, designated Bcg, Lsh, and Ity, which controls early microbial replication in reticuloendothelial organs. We have identified by positional cloning a candid...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192162/
https://ncbi.nlm.nih.gov/pubmed/7650477
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