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HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing

T cells are made tolerant only to those self-peptides that are presented in sufficient amounts by antigen-presenting cells. They ignore cryptic self-determinants, such as either those not generated by processing machinery or generated in insufficient amounts. It is anticipated that mechanisms that e...

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Bibliografske podrobnosti
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1995
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192056/
https://ncbi.nlm.nih.gov/pubmed/7760011
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