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CD28 signals through acidic sphingomyelinase
T cell receptor recognition of antigen can lead either to T lymphocyte differentiation and proliferation or to a state of unresponsiveness, which is dependent on whether appropriate costimulatory signals are provided to the mature T cell. We have investigated a novel intracellular signaling pathway...
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Format: | Artigo |
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Language: | Inglês |
Published: |
The Rockefeller University Press
1995
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192051/ https://ncbi.nlm.nih.gov/pubmed/7759998 |
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