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Suppression of erythro-megakaryocytopoiesis and the induction of reversible thrombocytopenia in mice transgenic for the thymidine kinase gene targeted by the platelet glycoprotein alpha IIb promoter [published erratum appears in J Exp Med 1995 Oct 1;182(4):1177]
The mechanisms that regulate the commitment of a totipotent stem cell to the megakaryocytic lineage are largely unknown. Using a molecular approach to the study of megakaryocytopoiesis and platelet production, mice in which thrombocytopoiesis could be controlled were produced by targeting the expres...
Gardado en:
| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
1995
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192050/ https://ncbi.nlm.nih.gov/pubmed/7760003 |
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