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Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro.

cis-Platinum compounds, which are used in cancer chemotherapy, are thought to exert their effect by damaging DNA. It is known that this damage is partially repaired in Escherichia coli. Using cis-Pt-treated pBR322 DNA as a probe, we investigated the role of nucleotide excision repair in the removal...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Husain, I, Chaney, S G, Sancar, A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219204/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3897194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.163.3.817-823.1985
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