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Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta

Tolerance of monocytes/macrophages to endotoxin (lipopolysaccharide [LPS]) can be induced both in vivo and in vitro by LPS itself. Exposure to LPS, even at a very low dose, induces a downregulation of cytokine response to a second high dose LPS challenge. To learn more about the unknown mechanisms o...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191997/
https://ncbi.nlm.nih.gov/pubmed/7722463
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