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Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice
CD8 is a cell surface glycoprotein on major histocompatibility complex class I-restricted T cells. Thymocytes and most peripheral T cells express CD8 as heterodimers of CD8 alpha and CD8 beta. The intestinal intraepithelial lymphocytes (IEL), which have been suggested to be generated extrathymically...
Guardat en:
| Format: | Artigo |
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| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191635/ https://ncbi.nlm.nih.gov/pubmed/8064243 |
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