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The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras
CD28 is a 44-kD homodimer expressed on the surface of the majority of human T cells that provides an important costimulus for T cell activation. The biochemical basis of the CD28 accessory signals is poorly understood. Triggering of the T cell antigen receptor (TCR) activates the p21ras proteins. He...
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| Format: | Artigo |
|---|---|
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
1994
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191634/ https://ncbi.nlm.nih.gov/pubmed/7520466 |
| Oznake: |
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