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The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

CD28 is a 44-kD homodimer expressed on the surface of the majority of human T cells that provides an important costimulus for T cell activation. The biochemical basis of the CD28 accessory signals is poorly understood. Triggering of the T cell antigen receptor (TCR) activates the p21ras proteins. He...

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書目詳細資料
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191634/
https://ncbi.nlm.nih.gov/pubmed/7520466
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