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Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells
The tumor necrosis factor alpha (TNF-alpha) gene is rapidly transcribed in activated T cells via a calcium-dependent pathway that does not require de novo protein synthesis, but is completely blocked by the immunosuppressive drugs cyclosporin A (CsA) and FK506. Here we show that calcineurin phosphat...
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| 格式: | Artigo |
|---|---|
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
1994
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191603/ https://ncbi.nlm.nih.gov/pubmed/8046352 |
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