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Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity

Mutations within the class I major histocompatibility complex (MHC) molecule that affect a peptide binding can result in strong allogeneic responses. It is believed this reflects, in part, binding of a different set of endogenous peptides by each MHC molecule. We have examined the representation of...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191347/
https://ncbi.nlm.nih.gov/pubmed/8270866
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