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The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes

Chediak-Higashi Syndrome (CHS) is an autosomal recessive disease affecting secretory granules and lysosomes-like organelles. In CHS fibroblasts, acidic organelles are abnormally large and clustered in the perinuclear area. We have analyzed fibroblast cell lines from a CHS patient and from the murine...

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Bibliografische gegevens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191291/
https://ncbi.nlm.nih.gov/pubmed/7902407
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