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Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues

Antigen-specific B cell responses to mucosally delivered proteins are dependent upon CD4-positive T helper (Th) cells, and the frequency of Th1 and Th2 cell responses after oral immunization may determine the level and isotype of mucosal antibody responses. We have used a protein- based vaccine, tet...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191217/
https://ncbi.nlm.nih.gov/pubmed/8376936
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