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Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome
Immunoglobulin (Ig) genes were isolated from unamplified conventional as well as polymerase chain reaction-generated cDNA libraries constructed from the peripheral blood cells of a patient with complete DiGeorge syndrome. Comparison of the sequences of 36 heavy chain clones to the recently expanded...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1993
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191178/ https://ncbi.nlm.nih.gov/pubmed/8350056 |
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