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Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis

Tumor necrosis factor (TNF) produced by tumor cells after gene transfer can effectively suppress the growth of locally growing tumors. We wanted to test the effects of "local" TNF on the growth of a highly metastatic cell line. Therefore, a recombinant retrovirus allowing expression of the...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191077/
https://ncbi.nlm.nih.gov/pubmed/8315391
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