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Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

Transgenic murine lines have been constructed that express a chimeric class I molecule composed of the alpha 1 and alpha 2 domains of HLA- A2.1 and the alpha 3, transmembrane, and cytoplasmic domains of H-2Kb. Upon immunization with influenza virus, transgenic mice developed a strong A2.1Kb-restrict...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190816/
https://ncbi.nlm.nih.gov/pubmed/1706750
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