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Human diseases of telomerase dysfunction: insights into tissue aging

There are at least three human diseases that are associated with germ-line mutations of the genes encoding the two essential components of telomerase, TERT and TERC. Heterozygous mutations of these genes have been described for patients with dyskeratosis congenita, bone marrow failure and idiopathic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garcia, Christine Kim, Wright, Woodring E., Shay, Jerry W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190725/
https://ncbi.nlm.nih.gov/pubmed/17913752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm644
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