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Poly(ADP-ribosyl)ation in mammalian ageing
Poly(ADP-ribose) polymerases (PARPs) catalyze the post-translational modification of proteins with poly(ADP-ribose). Two PARP isoforms, PARP-1 and PARP-2, display catalytic activity by contact with DNA-strand breaks and are involved in DNA base-excision repair and other repair pathways. A body of co...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190698/ https://ncbi.nlm.nih.gov/pubmed/17913748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm735 |
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