An Rgd Sequence in the P2y(2) Receptor Interacts with α(V)β(3) Integrins and Is Required for G(o)-Mediated Signal Transduction

The P2Y(2) nucleotide receptor (P2Y(2)R) contains the integrin-binding domain arginine-glycine-aspartic acid (RGD) in its first extracellular loop, raising the possibility that this G protein–coupled receptor interacts directly with an integrin. Binding of a peptide corresponding to the first extrac...

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Detalhes bibliográficos
Main Authors: Erb, Laurie, Liu, Jun, Ockerhausen, Jonathan, Kong, Qiongman, Garrad, Richard C., Griffin, Korey, Neal, Chris, Krugh, Brent, Santiago-Pérez, Laura I., González, Fernando A., Gresham, Hattie D., Turner, John T., Weisman, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190579/
https://ncbi.nlm.nih.gov/pubmed/11331301
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