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Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance

The relative susceptibility of neonatal and adult murine splenocytes to induction of B-cell tolerance was studied in vitro. Adult cells required approximately 1,000-fold more trinitrophenyl-human gamma globulin to be rendered tolerant than did cells from 9- to 12-day-old neonates. The potential effe...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190369/
https://ncbi.nlm.nih.gov/pubmed/1084409
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