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H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice

Lymphocytic choriomeningitis or vaccinia virus-immune spleen cells of H- 2 mutant mice carrying a point mutation in the K region (B6 H-2ba, B6 H- 2bf) cannot lyse infected wild-type H-2Kb targets and vice versa. Yet, cytotoxic T cells specific for infected H-2Kba or H-2Kbf targets are generated duri...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1976
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190113/
https://ncbi.nlm.nih.gov/pubmed/1082490
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