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The mechanism of tolerance induction in thymus-derived lymphocytes; I. intracellular inactivation of hapten-reactive helper T lymphocytes by hapten-nonimmunogenic copolymer of D-amino acids

Treatment of a p-azobenzoate (PAB) derivative of a copolymer of D- glutamic acid and D-lysine (D-GL) induced a profound state of unresponsiveness to PAB-reactive helper T lymphocytes generated in PAB- mouse gamma globulin (MGG)-primed mice. This unresponsiveness in T lymphocytes was specific for PAB...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1975
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189845/
https://ncbi.nlm.nih.gov/pubmed/47899
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