The snake venom metalloproteinase BaP1 induces joint hypernociception through TNF-α and PGE(2)-dependent mechanisms

BACKGROUND AND PURPOSE: Matrix metalloproteinases (MMPs) have been implicated in joint tissue destruction in arthritis. However, MMPs have not been assigned a role in joint pain. We investigated the ability of BaP1, a metalloproteinase from Bothrops asper snake venom, with structural homology to MMP...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fernandes, C M, de Fátima Pereira Teixeira, C, Leite, A C R M, Gutiérrez, J M, Rocha, F A C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189826/
https://ncbi.nlm.nih.gov/pubmed/17592506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707351
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