Thermodynamic analysis of ligands at cholecystokinin CCK(2) receptors in rat cerebral cortex

BACKGROUND AND PURPOSE: Several studies using radioligand binding assays, have shown that measurement of thermodynamic parameters can allow discrimination of agonists and antagonists (Weiland et al., 1979; Borea et al., 1996a). Here we investigate whether agonists and antagonists can be thermodynami...

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Main Authors: Harper, E A, Roberts, S P, Kalindjian, S B
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189820/
https://ncbi.nlm.nih.gov/pubmed/17592503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707355
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