Cannabidiol displays unexpectedly high potency as an antagonist of CB(1) and CB(2) receptor agonists in vitro

BACKGROUND AND PURPOSE: A nonpsychoactive constituent of the cannabis plant, cannabidiol has been demonstrated to have low affinity for both cannabinoid CB(1) and CB(2) receptors. We have shown previously that cannabidiol can enhance electrically evoked contractions of the mouse vas deferens, sugges...

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Bibliografiska uppgifter
Huvudupphovsmän: Thomas, A, Baillie, G L, Phillips, A M, Razdan, R K, Ross, R A, Pertwee, R G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189767/
https://ncbi.nlm.nih.gov/pubmed/17245363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707133
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