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Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia–reperfusion damage in the rat
BACKGROUND AND PURPOSE: Phosphodiesterase-5 inhibitors are beneficial in pulmonary hypertension and congestive heart failure, the two conditions associated with coronary heart disease and ischaemia. We investigated whether sildenafil counteracts the cardiovascular alterations induced by N (ω)-nitro-...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189760/ https://ncbi.nlm.nih.gov/pubmed/17245365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707131 |
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