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Synthetic peptide vaccine confers protection against murine malaria

A synthetic peptide, (DPPPPNPN)2D, representing a subunit of the repeat domain of the Plasmodium berghei circumsporozoite protein, was conjugated to tetanus toxoid using bisdiazobenzidine. Immunization of mice and rats with the conjugate induced high serum titers of antibodies to the parasite, and m...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189666/
https://ncbi.nlm.nih.gov/pubmed/3316473
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