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Prolactin Drives Estrogen Receptor-α-Dependent Ductal Expansion and Synergizes with Transforming Growth Factor-α to Induce Mammary Tumors in Males
Male breast cancer is rare and has been the focus of limited research. Although the etiology is unclear, conditions increasing circulating prolactin (PRL), as well as estrogen, increase the risk of tumorigenesis. We modeled exposure to elevated PRL in transgenic mice, using the mammary-selective, es...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Investigative Pathology
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189634/ https://ncbi.nlm.nih.gov/pubmed/18156207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070597 |
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