Acute Modulations in Permeability Barrier Function Regulate Epidermal Cornification : Role of Caspase-14 and the Protease-Activated Receptor Type 2

Stratum corneum comprises corneocytes, derived from outer stratum granulosum during terminal differentiation, embedded in a lipid-enriched extracellular matrix, secreted from epidermal lamellar bodies. Permeability barrier insults stimulate rapid secretion of preformed lamellar bodies from the outer...

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Autores principales: Demerjian, Marianne, Hachem, Jean-Pierre, Tschachler, Erwin, Denecker, Geertrui, Declercq, Wim, Vandenabeele, Peter, Mauro, Theodora, Hupe, Melanie, Crumrine, Debra, Roelandt, Truus, Houben, Evi, Elias, Peter M., Feingold, Kenneth R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2008
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189608/
https://ncbi.nlm.nih.gov/pubmed/18156206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070161
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