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Regulation of MHC class II gene expression in macrophages by hematopoietic colony-stimulating factors (CSF). Induction by granulocyte/macrophage CSF and inhibition by CSF-1

CSF-1 and granulocyte/monocyte CSF (GM-CSF) were shown to modulate the levels of Ia gene and protein expression in bone marrow-derived macrophages (BMM). Recombinant GM-CSF induced high levels of Ia expression, similar to the levels induced by INF-gamma, while IL-3 had no effect. In contrast, recomb...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189497/
https://ncbi.nlm.nih.gov/pubmed/2509625
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