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Demonstration of delta rec-pseudo J alpha rearrangement with deletion of the delta locus in a human stem-cell leukemia

It has been hypothesized that a rearrangement between the delta recombining element (delta Rec) and a pseudo J alpha gene serves to delete the TCR-delta locus before rearrangement of the TCR-alpha genes. We have now sequenced a direct, site-specific rearrangement between the delta Rec element and a...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189371/
https://ncbi.nlm.nih.gov/pubmed/2746162
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