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Clonal diversity in the B cell repertoire of patients with X-linked agammaglobulinemia

Ig protein and mRNA expression was examined in a collection of 18 monoclonal EBV-transformed B cell lines derived from five patients with X-linked agammaglobulinemia (XLA). A diversity of H and L chain isotypes were synthesized by these lines: the majority (12 lines) expressed mu kappa chains, while...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189345/
https://ncbi.nlm.nih.gov/pubmed/2786547
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