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CD4+ T cells are required for development of a murine retrovirus- induced immunodeficiency syndrome (MAIDS)

Mice depleted in vivo of CD4+ Th cells by treatment with mAb GK1.5 were found to be resistant to the lymphoproliferative/immunodeficiency disease (MAIDS) induced in intact mice by infection with the mixture of LP-BM5 murine leukemia viruses. Depleted mice did not develop lymphadenopathy or splenomeg...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189016/
https://ncbi.nlm.nih.gov/pubmed/2842430
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