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Plasminogen activator inhibitor 1 and 2 are tumor necrosis factor/cachectin-responsive genes
Human rTNF/Cachectin was shown to stimulate gene transcription of plasminogen activator inhibitor (PA1)-1 and PAI-2, and simultaneously suppress constitutive gene expression of tissue-type plasminogen activator (t-PA) in human fibrosarcoma cells. We propose that a TNF- mediated reprogramming of gene...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1988
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188989/ https://ncbi.nlm.nih.gov/pubmed/3137305 |
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