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C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha

We have demonstrated that purified C5a is a potent stimulus to human PBMC secretion of TNF-alpha, IL-1 beta, and IL-1 alpha, which proceeds in a dose-dependent fashion. At a given concentration of C5a, TNF-alpha and IL-1 beta secretion did not differ significantly; both were secreted in significantl...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1988
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188974/
https://ncbi.nlm.nih.gov/pubmed/3260938
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