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The kappa-deleting element. Germline and rearranged, duplicated and dispersed forms
Human light chain genes are used in a kappa before lambda order. Accompanying this hierarchy is the rearrangement of a kappa-deleting element (Kde) which eliminates the kappa locus before lambda gene rearrangement. In approximately 60% of rearrangements the Kde recombines at a conserved heptamer wit...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1988
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188845/ https://ncbi.nlm.nih.gov/pubmed/3126251 |
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