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The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells
Mice transgenic for a c-myc gene driven by the IgH enhancer (E mu-myc) were shown to almost invariably develop lymphomas, 90% succumbing in the first 5 mo of life. The tumors typically presented as rapidly progressive lymphadenopathy with thymic involvement and were highly malignant by transplantati...
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| Materialtyp: | Artigo |
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| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
1988
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188841/ https://ncbi.nlm.nih.gov/pubmed/3258007 |
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