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CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells

A novel pathway of IgE-B cell differentiation has been identified. Engagement of the B cell antigen CD40 by F(ab')2 fragments of monoclonal antibody (mAb) 626.1 in the presence of recombinant interleukin 4 (rIL-4) induced intense IgE synthesis, but modest IgG synthesis, by highly purified human...

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Bibliografische gegevens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188752/
https://ncbi.nlm.nih.gov/pubmed/1701824
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