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Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages
Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity. These drugs, azidothymidine (AZT), dideoxycyti...
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| Format: | Artigo |
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| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1987
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188703/ https://ncbi.nlm.nih.gov/pubmed/2821152 |
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