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Introduction of H-2Dd determinants into the H-2Ld antigen by site- directed mutagenesis

We used site-directed mutagenesis to localize serologically defined (s) and CTL (c)-defined alloantigenic determinants to discrete amino acid sequences of a murine MHC class I antigen. Based on the prediction that amino acid position 63-73 of the H-2Dd antigen forms s- allodeterminants, the H-2Ld ge...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188688/
https://ncbi.nlm.nih.gov/pubmed/2442290
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