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Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus

Elimination of potentially self-reactive T lymphocytes during their maturation in the thymus has been shown to be a major mechanism in accomplishing self-tolerance. Previous reports demonstrated that clonal deletion of self-Mls-1a-specific V beta 6+ T lymphocyte is controlled by a radiosensitive I-E...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188660/
https://ncbi.nlm.nih.gov/pubmed/2230645
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