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Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain

Two prior studies with a small number of T cell lines have shown that the presentation of native protein antigens by epidermal Langerhans cells (LC) is regulated. When freshly isolated, LC are efficient antigen-presenting cells (APC), but after a period of culture LC are inefficient or even inactive...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188653/
https://ncbi.nlm.nih.gov/pubmed/2121888
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