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Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor

High-affinity IL-2-R correspond to a membrane receptor complex composed of two different IL-2-binding proteins, the Tac antigen (alpha chain) and a 70-75 kD beta chain. Using cell lines that express either the alpha or the beta protein, we demonstrate that IL-2 internalization occurs when ligand is...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188578/
https://ncbi.nlm.nih.gov/pubmed/3031195
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