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Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization

We have obtained the complete variable region mRNA sequences of 11 LPS- derived and 14 secondary immunization-derived monoclonal IgM anti-IgG antibodies (rheumatoid factors, RFs). A comparative analysis of these sequences showed that monoclonal RFs derived after polyclonal activation are structurall...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188567/
https://ncbi.nlm.nih.gov/pubmed/3494096
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