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Secretion of pyruvate. An antioxidant defense of mammalian cells
Cells in culture are exposed to marked oxidative stress, H2O2 being one of the predominant agents. Pyruvate and other alpha-ketoacids reacted rapidly, stoichiometrically, and nonenzymatically with H2O2, and they protected cells from its cytolytic effects. All five human and murine cell types studied...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188509/ https://ncbi.nlm.nih.gov/pubmed/3102672 |
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